Applications
Each area below opens the PhotoSound publications gallery, filtered to that category and to TriTom. Application notes and presentation excerpts are on this page as PDFs.
- Anatomical Imaging Whole-body reference anatomy from endogenous contrast alone — circulatory system, internal organs and skin — at 150 µm in transverse planes. Publications on photosound.com ↗
- Cancer Imaging Tumour growth, vascular morphology, total haemoglobin and detection of metastasis, followed longitudinally in the same animal. Publications on photosound.com ↗
- Cardiac Imaging The thoracic region resolved in three dimensions: heart, thoracic aorta and internal thoracic arteries, without contrast agents or ionizing radiation. Publications on photosound.com ↗
- Cellular and Molecular Imaging Targeted probes and labelled cells mapped onto the animal’s own anatomy, with sensitivity to 100 nM ICG photoacoustically and below 3 nM IR-780 by fluorescence. Publications on photosound.com ↗
- Contrast Agent Development Screen up to ten 50 µL samples per scan in the cuvette holder, then follow the same agent in vivo. Multiwavelength sequences unmix several absorbers at once. Publications on photosound.com ↗
- Custom Systems and Algorithms Open data formats — raw and mat for scan data, vtk for volumes — so reconstruction and analysis work can run on TriTom data outside the supplied software. Publications on photosound.com ↗
- Developmental Biology Placental function and fetal vascular development monitored across gestation, including acute response to vasoactive therapy in maternal vasculature. Publications on photosound.com ↗
- Disease Monitoring Repeatable positioning and 36-second scans make serial imaging of the same animal practical, so progression and recovery are measured rather than inferred. Publications on photosound.com ↗
- Multimodal Imaging The Premium edition acquires photoacoustic and fluorescence data co-registered in time and space — molecular sensitivity and anatomical context from one scan. Publications on photosound.com ↗
- Neuroimaging Superficial and deep brain structures — jugular vein, brachial and ophthalmic arteries, confluence of sinus, cerebral artery — with a dedicated brain scan holder. Publications on photosound.com ↗
- Phantom Development Tissue-mimicking phantoms and the supplied phantom kit for characterising resolution, sensitivity and quantitative accuracy before moving to animals. Publications on photosound.com ↗
- Radiation Acoustics Acoustic detection of ionizing radiation, built on the same LEGION parallel data acquisition that runs TriTom’s photoacoustic channel. Publications on photosound.com ↗
- Therapeutic Monitoring Measure what a drug or therapy actually does: intensity and duration of vasodilation, changes in oxygenation, tumour response over a treatment course. Publications on photosound.com ↗
- Tissue Engineering and Regeneration Track labelled cells after delivery — contrast-loaded mesenchymal stem cells have been imaged in an excised rat spinal cord at known injected volumes. Publications on photosound.com ↗
Application notes and excerpts
Longer write-ups of specific studies, and the presentation slides that go with them.
- Label-free vascular imaging and anatomical referencing Whole-body imaging of hairless and nude mouse models, with the heart, liver, spleen, aorta, kidneys and brown adipose tissue identified.
- Liver and kidney Coronal and transverse 5 mm sections through the liver and right kidney at 0.15 mm resolution.
- One-page TriTom flier Depth, resolution, scan time and which agents and biomolecules are visible, in short form.
Not sure which fits your study?
Send us your model, probe and endpoints and we will tell you whether TriTom can measure what you need.